Chemical Castration of Adult and non-Adult Male Dogs with Sodium Chloride Solution

This study evaluated intra-testicular injection of sodium chloride for chemical-castration in 12 mix bred dogs (6 adult and 6 non-adult). The sodium chloride at 20% concentration per testis were injected intratesticularly until tension occurs and the testicles were removed with the open surgical technique about 30 days for histopathologic evaluation. Testicular swelling was evident in both group dogs following injection and reached peak within 48 hours. While testicular volume decreased significantly (P<0.05) in both group after 2-4 weeks. The testicles underwent atrophy at the 30 th day in non-adult group with nomarked alteration in adult group. Though only 3 non-adult dogs were sterile, other adult dogs maintained androgenesis. It was concluded that intra-testicular injections of sodiumchloride at 20% concentration administration may not be accepted as a suitable alternative to the open surgical technique for castration in adult dogs but could be used as a preferable treatment option non adult dogs.